For the sixth time as collaborators since 2002, Martin Scorsese and Leonardo DiCaprio will team up for a new film, Devil in the White City, in which the 40-year-old actor will portray notorious Chicago serial killer, Dr. H.H. Holmes.

Holmes is widely known for having killed up to 200 people in a hotel during the 1893 World's Fair. His "murder castle" was equipped with its own crematorium, gas chamber and dissecting table where his victims would be murdered. Holmes was partial to younger females and was known to have sold skeletons to science.

The impending film is based upon Erik Larson's 2003 novel, The Devil In The White City: Murder, Magic And Madness At The Fair That Changed America, which boasts an elaborate spin on real-life happenings. Scorsese will direct the script penned by Billy Ray, known for his involvement with The Hunger Games, Captain Phillips and Flightplan, while DiCaprio will sit in the producers chair, Deadline reports.

For several years, the Titanic actor has shown great interest in creating a film adaptation of the Larson novel. DiCaprio gained rights to the film back in 2010 and after Paramount recently won the bid for the film, DiCaprio's long-time plan can finally spring into action. At one point, actor-director duo Tom Cruise and Kathryn Bigelow were close in line for their own adaptation.

Scorsese and DiCaprio are hardly strangers after having collaborated on The Aviator, The Departed, Gangs of New York, Shutter Island and The Wolf of Wall Street. Although he's yet to take the golden statue of approval home after endless blockbusters, he's been nominated for his portrayls in The Aviator as well as The Wolf of Wall Street.

In the mean time, DiCaprio has announced plans to turn an island, Blackadore Caye, into an environmentally friendly resort while Scorsese takes on a new HBO project alongside Mick Jagger, called Vinyl. According to Consequence of Sound, a White City release date has yet to be unveiled but with it being next on Scorsese's list, development should start up rather shortly.

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